>>11408797Those are numbers that somebody literally pulled out of their ass, doing no research whatsoever, and nobody has ever seen copper as important enough to revisit them. All animal research suggest far higher requirements.
Some of the improtant copper enzymes:
Ceruplasmin distributes copper across the body. May also be important to some degree for iron regulation.
Cytochrome c oxidase This enzyme is why cyanide is toxic. You will basically suffocate on the celular level without it. Deficiency in it may cause brain atrophy and general weakness.
Dopamine beta-hydroxylase involved in many things, primarily involving the conversion of dopamine to norepinephrine. deficiency will result in greatly increased dopamine levels in the body, reduced ability to produce glucose in liver, inability to turn on brown fat (impaired thermogenesis), sodium loss and increased speed fo digestion, poor tolerance to excercise, and general brain fog or inability to act despite the urge to do so.
Hephaestin. Iron homeostasis.
Lysil oxidase. Crosslinking of collagen. Deficiency results in poor health of skin, bone, ligament and blood vessels. The reason why most anti aging creams contain copper. Might be the cause of aneurysms.
Primary amine oxidase. Not well understood, but fat cells with this enzyme disabled bloat incontrollably. Deficiency may thus be the primary cause of obesity. (carnitine palmitoyltransferase might also be. It isn't known to need copper, but appears to be affected, the fact that liver has its own version of this enzyme might explain why affected people are still able to burn fat through ketosis)
Tyrosinase. Required for the production of melanin. Might explain the prejudice about darker skin, as people with darker skin waste por copper on producing the pigment, meaning that everybody being comparably Cu deficient, ligther people may be smarter and healthier than darker people due to having more copper to spare for other metabolic processes.
