>https://www.ncbi.nlm.nih.gov/pubmed/27996938
>decreasing the function of CCR5 increases MAPK/CREB signaling, long-term potentiation (LTP), and hippocampus-dependent memory
>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412887/
>large genome-wide association studies have identified 13 susceptibility gene variants for migraine with and without aura (Anttila et al., 2010, 2013; Chasman et al., 2011; Freilinger et al., 2012), three of which regulate glutaminergic neurotransmission ... and two of which regulate synaptic development and plasticity
>Given that 2 of the 13 susceptibility genes regulate synaptic development and plasticity, it is reasonable to speculate that some of the networks mentioned above may not be properly wired to set a normal level of habituation throughout the brain
>https://neurohacker.com/what-is-glutamate
>Glutamate plays a prominent role in neural circuits involved with synaptic plasticity—the ability for strengthening or weakening of signaling between neurons over time to shape learning and memory. It’s a major player in the subset of plasticity called long-term potentiation (LTP).
>https://www.nature.com/articles/6363690
Notably, it appears that the CCR5 deletion demonstrated particularly strong selection in Ashkenazi jews as well, 13.4%, which is significantly higher than even the general rate of CCR5 (about 10%) in Europe. In fact, it's unrealistically high, given that they performed next-to 0 interbreeding with non-jews.
All of this leads me to believe that there is a very strong correlation between MSG sensitivity, migraines, intelligence and learning; however, that's not to say that CCR5 is the only gene that encodes for intelligence. Will these be the genes we target for trans-humanism? Discuss.
>decreasing the function of CCR5 increases MAPK/CREB signaling, long-term potentiation (LTP), and hippocampus-dependent memory
>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412887/
>large genome-wide association studies have identified 13 susceptibility gene variants for migraine with and without aura (Anttila et al., 2010, 2013; Chasman et al., 2011; Freilinger et al., 2012), three of which regulate glutaminergic neurotransmission ... and two of which regulate synaptic development and plasticity
>Given that 2 of the 13 susceptibility genes regulate synaptic development and plasticity, it is reasonable to speculate that some of the networks mentioned above may not be properly wired to set a normal level of habituation throughout the brain
>https://neurohacker.com/what-is-glutamate
>Glutamate plays a prominent role in neural circuits involved with synaptic plasticity—the ability for strengthening or weakening of signaling between neurons over time to shape learning and memory. It’s a major player in the subset of plasticity called long-term potentiation (LTP).
>https://www.nature.com/articles/6363690
Notably, it appears that the CCR5 deletion demonstrated particularly strong selection in Ashkenazi jews as well, 13.4%, which is significantly higher than even the general rate of CCR5 (about 10%) in Europe. In fact, it's unrealistically high, given that they performed next-to 0 interbreeding with non-jews.
All of this leads me to believe that there is a very strong correlation between MSG sensitivity, migraines, intelligence and learning; however, that's not to say that CCR5 is the only gene that encodes for intelligence. Will these be the genes we target for trans-humanism? Discuss.
