>>11320804semen is made of sperm and mixes with various fluids secreted by different glands of the ejaculatory duct, with a notable contributor being zinc, your body stores a lot of zinc throughout the body, including the brain, theoretically, if you ejaculate a lot, your zinc will be lost so it will need to be replaced, from doing cursory reading, your zinc stores are in your blood plasma (and liver) where they are attached to metal carrier proteins. It is theoretically possible in my estimation, that by lowering your zinc levels enough via constant ejaculation, you will not have enough for the brain which might cause symptoms. However the level of ejaculation required to produce a measurable effect is unknown.
The more important theoretical benefit of semen retention is that testosterone produced by your Leydig cells will not be used to support the constant replenishing of your stores of sperm as you are constantly ejaculating them, and perhaps that testosterone may go to the rest of your body and aid in other anabolic processes. Evidence supporting higher testosterone levels with semen retention are limited, the 1 study people always quote about the 7 day spike is a worthless chinese study with a limited number of healthy males. A serious study would look for a MUCH larger period of time and be a lot more well designed with a few more people.