Genes/Proteins of size recent research

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Did anyone know|can tell about recent recearch in field of size of mammals and which substance influences it?
There are few known substances like somatotropin, insulin like growth factors etc, also there are some known genes that related to growth.
Did anyone try to grow mice or pigs 10 times larger by mass than normal for example?
Were there attempts in proportional enlargement of humans? (even if only adolescent)