>>11255524This is not the limit, there is an enzyme native to the body and cells that have it active; it's only when you have an isolated tissue outside the organism where this becomes an issue; it's almost certainly a mechanism to prevent cancer. Really nothing to solve here.
The biggest killer right now is the calcium magnesium imbalance.
You always need more magnesium than calcium, otherwise it kills you; the calcium either accumulates, causing calcifications, or its excretion drains magnesium from the body and causes widespread disfunctions. (there is no way to directly measure this as plasma levels are kept always stable) The extreme levels in our food gets body stuck in an endless fight to get rid of the calcium (which apparently requires magnesium, two mol per one mol excreted) and keeping enough magnesium for basic bodily functions.
What makes people who live to 110+ different from the rest is that they don't suffer from diseases related to this. They either follow weird diets that prevent this from occuring, or have a beneficial mutation that helps the body to deal with the problem in some way.
The body keeps massive reserves, so it may take a year + to fix, even with a lot of Mg and very little Ca, but you will eventually start getting somewhat younger eventually and the accompanying diseases start to dimnish.
Fasting may allow the body to fix it, but it still needs to be fixed in food.
