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I notice that I'm much happier and more alert after a short period of regular coffee intake (a week or two or so), but after that the effect starts to diminish and I eventually end up unable to function well without coffee, and without experiencing the early euphoria. If I don't drink coffee for a week or so, then a single cup can keep me awake and alert for two days with no sleep. I might be unusually sensitive to stimuli, though, and I've never tried any other artificial stimuli.
