>>11290260>Do you mean to say that regular E. coli found in the microbiota is the same as O157:H7No, I meant O157:H7 is ubiquitous enough to be ingested by everyone with the passage of time. Yet, they only cause pathologies when they are in outside a tolerant host (cow & sheep intestines) and in human intestines, in certain concentrations and conditions.
O157.H7 is apparently easily defeated by the environment of outer skin layers, with their enzymes, and competing E coli. and other lifeforms.
Other potentially harmful e.coli are normally in and on us, as well as Staph. aureus and H.pylor, with more virulence factors. But unless- here is the important part- unless the virulence factor somehow gives the bacteria an evolutionary advantage against other, nearby fast-growing bacteria, those virulence factors will not be conserved, making the novel evolution of a bacteria with a novel virulence factor HIGHLY unlikely.
And since these strains are ubiquitous at low CFU, existing in people with no symptoms. Disease is a breakdown in a system. In a normal situation, a normal person, a normal amount of bacteria- no symptoms, no disease, no pathology.
E. Coli, with new virulence factors found in patients or in the environment, should be reported to the CDC
