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Tons do, the issue is you gotta remember that your body has limits for a reason, take them away and you risk damage, and the benefits don't "stack" eg taking more decreases performance.
My picks for 1/2-1/4 dose to boost are:
>Anxiety free super Chad. -benzos
>Creativity boost -psychadelic microdose
>Focus and joy - Adderall
>Energy -caffeine
>Remove pain - opiate
Most of these have legal sources or "nootropic"/RC subsitutes and if you only touch them once a month or so tops and don't ever increase the dose or frequency they can help you get that extra 5% or deal with extraordinarily uncomfortable situations. There's a reason pilots have speed pills in survival kits. Also see German D-IX / pevertin.