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I'm microdosing memantine, dxm, bupropion and cph.
All of it is over the counter, the combo gives good effects at low doses from all being targeted by CYPD26. It does NMDA, mildly SRSI, norepinephrine, nicotinic and acetylcholine effects.
I take 1/4 of a dose of each, just once in the morning on an empty stomach, that's like from 1/8 to 1/16 of the common daily therapeutic dose. Side effects are minimum and go away after a week, when you'll feel the full effects. Side effects for me were funny cartoon dreams, bad memory and slurred speech, but went away after a week and only affected me for a couple of hours.
It's a combo and dosage that's not tough but needs daily dosing because of how the brain regulates itself. I'm also pairing it with HIIT exercise routines, healthy diet, supplements and good sleep, but without the meds it would not help at all. Bupropion also helped me to quit smoking tobacco, and keeps me fine because it has nicotinic targeting.
This combo It took away my pernicious depression and anxiety after a couple of months. Sometimes I put Tylenol to the combo because it has cannabinoid effects besides the NSAID and depression has an inflammatory immune component, but if you can get some cannabis to microdose that's fine also.
