Hello /sci/ neurobio undergrad here,

I've been doing a lot of reading about gene mutations that result in spliceosomal dysfunction; symptomatic of multiple neurological diseases.

Anyone aware of possible hypothetical treatments that would be able to restore the mutated, coded region of the spliceosome back to it's functional form.

I thought of using CRISPR/cas9, but that wouldn't be possible (unless you start from the zygote), right?