>>11121448This completely misses the point, which is to "tend one's own garden". Even if life rises again, it is at such a remove from ourselves, that it is irrelevant to us. The point is to eliminate ourselves in the present moment, ensuring that no one escapes. Especially to ensure that no on escapes into biological immortality. OP, you have my full support.
The obvious choices are nukes and germs, but unfortunately, humanity are a remarkably resiliant and cooperative pestilence. What is necessary is to make impossible the objective possibility of their reproduction, a tall order. If I could fling the Earth into the Sun, I'd do it, but this isn't a tenable solution. Let's continue brainstorming.
What is the absolute choke point of human reproduction, and consequently the human species itself? Human female eggs. Better yet, only a subset of human females have to be targeted-fertile women. I like to imagine simply teleporting them out of women's bodies on a continuous basis, but a disease which targets female reproductive capacity/egg production is a good thing to look into.