>>11071326glad to help. it's also worth noting that a lot of the work that goes into making GMOs actually has nothing to do with CRISPR or other gene editing techniques. most of the time we're not trying to knock out an endogenous site, we're trying to move traits from one cultivar to another.
for example - say you have a grain variety that grows well, but is super susceptible to disease. You look in the wild and see a cultivar of the same species that you'd never want to grow for a crop, but is super resistant to the disease that's giving you trouble. you figure out which genes are responsible for the disease resistance, stack them up in one plasmid, and transform them into the agriculturally valuable but disease-susceptible variety. the plasmid integrates into the genome in a random location, and as long as it doesn't land in anything important, you've got your GMO.
