Why is /sci/ such bio-cels? (Get it? Bio-incels... hehehe).
>A generally shallow free-energy landscape implies that the average structures and dynamics of DNA and RNA systems are easily perturbed and shifted by even weak-binding agents and altered solvent conditions. Indeed, the response to bending per- turbation is an attribute that nature can use for recognition pur- poses (3–5). However, small molecules and ions also are crucially important, either as structurally defined elements (water bridges, magnesium or spermidine ions at specific positions in condensed DNA, etc.) or for their effect on the dielectric medium around the molecule, with less-well-defined interaction structures.
Right now there are students all over the world who are being taught that 5’—AAUUTAA is bound to a homologous strand with individual “twisted” hydrogen bonds. That’s wrong.
