What does /sci/ think of the glutamate system of the brain? It's the brain's main excitatory system and its dysfunction may cause schizophrenia, depression, ADHD and brain fog for example. Research is building up but it's still nowhere near as studied as the dopamine or serotonin systems.

Examples of drugs that boost glutamate function: fasoracetam, N-methylglycine, DMG, TMG, d-serine.
Some drugs that reduce glutamate function: memantine, NO, ethanol.