>>10848258no. not in my experience. Ive been getting high every night for the past 8 years and am about to complete my PhD, working an average of eh, 65-70 hours a week for the past 5 years. No issue with memory, cognition, creativity. Helps avoid burnout. Only do it after all is done, I usually think about experiments or my project while reallllly stoned.
Also do acid and MDMA irregularly, about four times a year