>>13353688>Do you have any concerns over the lack of testing and the possible unforseen side effects this could result in?Of course, we can't see into the future. I'm not vaccinated myself, though that may change if things start looking worse heading into next winter or if novavax appears efficacious and safe.
>>13353789>You do realise vaccine efficacy is a complete abuse of RRR to make things look more effective than they are right? Look at the actual ARR and NNV. I'm not a sinovac shill, but it's ridiculous to compare mere percentage points and call that great.I'm well aware of RRR and ARR. The fact is the mRNA vaccines will prevent infection (whether asymptomatic or symptomatic) upon 80-90% of exposures. Sinovac at best will prevent severe infection at about the same rate, but who knows what efficacy is for preventing asymptomatic infection as well since I'm not aware of any study where the population received weekly testing.
>>13353789>This can be safely discarded as it's absolute numbers we care about, i.e. NNV and ARR, which are in reality about 1-2%I believe we've argued before, maybe not, but ARR is an absolute shitty measure to use for short term studies. Your chance of getting the flu in the next week are slim, yet your chance of getting the flu in the next decade are high.
>Again, are we vaccinating based on lab values now? Are we vaccinating to chase specific antibody levels and in vitro results?How else are you going to look at the diverse immune response?
>Why are these studies not looking at clinical infection?There's studies looking at those as well, including among health care workers and military members, and protection using mRNA vaccines or from prior infection appear equivalent, so I'm not sure where you're going with this...
By all means it appears that at least the mRNA vaccines are providing a broad enough immune response to protect against the mutating variants. That's true until it's not true, and it's not true yet.