Greetings to all whom I'll enlighten about the notion of Vagina Spiders: Vagina spiders are in some ways similar to STDs known as crabs. The only difference between vagina spiders and crabs is vagina spiders make webs in the vagina; this can be detrimental when having sexual intercourse. This is all because vagina spiders are very territorial creatures; vagina spiders will bite the penis and can infect the penis. Now, the best way to get rid of vagina spiders is to clean the vagina and apply a lotion inside the vagina; be sure to get rid of the webbing you find within the vagina. Wait for 24 hours before having sex with your partner.