>>14382834To make it very simple there are typically two different issues. Low amount of dopamine receptors in the frontal cortex or too many neurotransmitter (dopamine) transporters. The problem can be a combination of both. Amphetamine mimics dopamine while methylphenidate locks your own dopamine in the receptor so it cannot be withdrawn with neurotransmitter transporter.
>>14384703Stop taking it for a week and it will work again. Amphetamine and methylphenidate is not supposed to work forever, it is supposed to give you a window to organize your life while it works so that you can live normally when it stops working. If you start increasing dose you've already lost.
