>>14307825Initially I thought, "too complicated can't be done for centuries" since we don't really know all the details of what makes a male brain "male" and the only ways we can modify adults in vivo would be through gene therapy or transplantation; the former wouldn't work because we don't know which genes we'd change and the latter wouldn't work for obvious immunological reasons. But maybe if we got a female embryo going, but were able to replace all neural precursor stem cells with otherwise identical cells to the original female, but XY instead of XX, maybe that could work. I wonder if a female with a male nervous system even makes any sense. An interesting proposal, OP. Off the top of my head, I could name a lab or two that probably would be able to at least attempt an experiment like that in mice or even pigs.