>>14251795Took way to long for this to show up.
I work in drug discovery, we're currently entering a psychedelic renaissance. A couple of landmark papers in the past few years showed 1) that psychedelics are really effective at breaking opioid abuse habits, 2) that the induced neuritogenesis in the pre-frontal cortex is necessary for the anti-addictive properties of psychedelics, and 3) that analogs of a psychedelic were made that did not have psychedelic experiences but still induced neuritogenesis (these new molecules are dubbed psychoplastogens) . This was in vivo btw, not just cells-in-a-dish, so it's pretty established that this is the case. It's unclear the exact mechanism, but it seems to work through 2-ht2 receptors, most probably involving a and c.
We've put in a grant to find more of these.
