I take daily 150mg venlafaxine with 350mg quetiapine seroquel as meds. A friend gave me tramadol which I know is seretonergic.

I usually take only kratom and tianeptine as opioids. How dangerous is taking tramadol with my meds? I have 3 pills of 50mg tramadol HCl.

I had serotonin syndrome once before. I first had a combination of modafinil, venlafaxine, quetiapine, tianeptine, kratom . This was fine until I drank a large cup of Kanna (Sceletium tortuosum) which induced the syndrome .

Can I take the tramadol with my venla and suzieQ?