Pfeizer trial all cause mortality

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How do you respond to people that have either seen this video from the CCA https://www.canadiancovidcarealliance.org/

OR have read the BNT162b2 clinical trial published in the NE journal of medecine. I'm not great with statistics, but im assuming that the trial groups of ~20,000 are of sufficient size for whatever effects recorded (like %adverse) would be reflected in the global population after the rollout, right?