>>14117774https://pubmed.ncbi.nlm.nih.gov/7189278/“Twin female infants were fed 120 gm of chicken liver homogenate daily for four months. They developed irritability, vomiting, and bulging anterior fontanelles. Computed tomograms of the brain revealed enlarged ventricles in both infants and dilated subarachnoid spaces in one. Plasma vitamin A concentrations were elevated.”
https://pubmed.ncbi.nlm.nih.gov/3655980/“The younger brother of patient 1 had recurrent exudative otitis beginning at 5 months of age, requiring myringotomies and intermittent antibiotic therapy. Otitis media characterized by a profuse black exudate recurred at age 2 1/2 years, accompanied by lymphadenopathy, leg pain, and nausea. Limp, vomiting, and fever ensued, and papilledema was noted.
Diet included chicken liver spread two to three times a week, but did not differ from that of the parents or the healthy sister. Radiographs revealed splayed cranial sutures, but long bones were normal. A cranial CT scan revealed mild nonobstructive hydrocephalus.
By age 3 1/2 years, hepatomegaly, splenomegaly, and ascites were present, as were nausea, vomiting, bone pain and tenderness, lethargy, and otorrhea. By age 3 4/12 years, alopecia; a shiny, erythematous, exfoliative rash; and pleural effusion developed.”
