/sci/ - Science & Math » Thread #14068153

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Anonymous Fri 07 Jan 05:07:11 2022 No.14068153 View Reply Original Report

Quoted By: >>14068183

Nootropic and antidepressant thread, post your stacks and discuss new pharmacotherapies for cognitive decline.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187532/
Is oxymetazoline a viable nootropic?
Brexpiprazole and fluvoxamine looks like the best antipsychotic and SSRI respectively
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558054/
https://pubmed.ncbi.nlm.nih.gov/20373470/
Nicotine gum too ofcourse

Anonymous

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Anonymous Fri 07 Jan 2022 05:10:32 No.14068160 Report

Quoted By:

Brexpiprazole is an a1 blocker, potent a2c antagonist and 5ht1a agonist

Anonymous

Anonymous Fri 07 Jan 2022 05:26:51 No.14068183 Report

Quoted By:

>>14068153
Oxiracetam + CDP-choline is my go-to powerhouse for exams and college work, it's hard to beat honestly. Flmodafinil + F-phenibut + Bromantane + Phenylpiracetam makes you feel like a living god but dosing is tricky. Afobazole + black seed oil + tribulus terrestris + creatine + green tea is a good daily stack to reduce stress and increase overall well-being. L. reuteri is a great probiotic for overall health and cognitive function. Cod liver oil is extremely rich in omega-3, and vitamins A+D and one weekly serving makes a huge difference with regards to overall health over time. Also don't forget to supplement with a good source of magnesium (citrate, bisglycinate, threonate).

Anonymous

Anonymous Fri 07 Jan 2022 05:28:15 No.14068186 Report

Quoted By: >>14070563

I drink a gallon of coffee in the morning.

Anonymous

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Anonymous Fri 07 Jan 2022 06:11:00 No.14068287 Report

Quoted By: >>14068322

>4 x energy drink
>3 x progynova 2mg
>1 x microgest 100mg
>2 x spiractin 25mg

Anonymous

Anonymous Fri 07 Jan 2022 06:27:32 No.14068319 Report

Quoted By:

magic mushrooms actually work to improve mood and expand ability to solve problems

Anonymous

Anonymous Fri 07 Jan 2022 06:30:49 No.14068322 Report

Quoted By: >>14068331

>>14068287
>4, 3, 1, 2

Anonymous

Anonymous Fri 07 Jan 2022 06:30:50 No.14068323 Report

Quoted By:

is some snake oil salesman paying to have this same thread reposted daily?

Anonymous

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Anonymous Fri 07 Jan 2022 06:34:05 No.14068331 Report

Quoted By: >>14068341

>>14068322
Wanna make a guess if I put them in that order just to make some number autist's head overcook? I am evil incarnate...
https://www.youtube.com/watch?v=ZzLP0PGnHRI

Anonymous

Anonymous Fri 07 Jan 2022 06:41:05 No.14068341 Report

Quoted By:

>>14068331
slut

Anonymous

Anonymous Fri 07 Jan 2022 15:56:27 No.14069485 Report

Quoted By:

Anything about Bacopa monnieri? The wikipedia page on nootropics claims there's evidence for cognitive improvement on long term use, but I'd like to know if anyone has first hand experience as well. Looking at the archives it seems to be regarded positively as well.

Anonymous

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Anonymous Fri 07 Jan 2022 20:36:10 No.14070563 Report

Quoted By:

>>14068186
Cortisol through the roof then, also you gonna be pissing out all your body's mineral reserve since caffeine is a diuretic. Also invest in L-Theanine supplement if you really go that crazy on coffee. L-Theanine is a GABA modulating
analog of the amino acids glutamate and glutamine. Its derived from Green Tea or Gyokuro leaves, and the GABA modulation synergizes with caffeine like no other making it way less jittery, and also making crashes minimal to non existant.
Further elaboration, "This compound is used as anootropicfor its calming and relaxing properties. It is often taken in combination withcaffeineas it has been shown to mitigate its negative aspects, such asanxiety,increased blood pressureanddiminished sleep quality, while possibly improving upon the positive aspects.[4][5][6][7]Its ability to enhance attention has been repeatedly verified.[8][9][10][11][12][13][14]
A recent systematic review of the effects of theanine and caffeine has confirmed that the combination seems to improve aspects of attention.[15]The combination of L-theanine and caffeine may improve attention more than caffeine alone.[16][17]" Also cortisol levels are highest when you first wake up, so do your body and mind a favor by only caffeinating 1hr after waking up.

Source: psychonautwiki.org

Anonymous

Anonymous Sat 08 Jan 2022 02:43:09 No.14071965 Report

Quoted By: >>14071972

OP here, oxymetazoline definitely has a mild stimulant effect and it alleviates orthostatic hypotension/dizziness from my brexpiprazole, so far so good.

Anonymous

Anonymous Sat 08 Jan 2022 02:44:48 No.14071972 Report

Quoted By:

>>14071965
https://go.drugbank.com/drugs/DB00935/clinical_trials?conditions=DBCOND0033476%2CDBCOND0028921&phase=1&status=completed

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