Omicron came from mice

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>We found that the Omicron spike protein sequence was subjected to stronger positive selection than that of any reported SARS-CoV-2 variants known to evolve persistently in human hosts, suggesting a possibility of host-jumping. The molecular spectrum of mutations (i.e., the relative frequency of the 12 types of base substitutions) acquired by the progenitor of Omicron was significantly different from the spectrum for viruses that evolved in human patients, but resembled the spectra associated with virus evolution in a mouse cellular environment. Furthermore, mutations in the Omicron spike protein significantly overlapped with SARS-CoV-2 mutations known to promote adaptation to mouse hosts, particularly through enhanced spike protein binding affinity for the mouse cell entry receptor. Collectively, our results suggest that the progenitor of Omicron jumped from humans to mice, rapidly accumulated mutations conducive to infecting that host, then jumped back into humans, indicating an inter-species evolutionary trajectory for the Omicron outbreak.
t. https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8702434/
This seems to indicate that it will be impossible to inject our way out of the pandemic. It's not possible to capture and vaccinate every mouse on the planet and even if we could, there are plenty of other mammals that can serve as hosts and mutagens.
Does this mean the injections go away? Or does it mean an increase in how often they are required, with each new animal source mutation getting its own formulation? The new "soccer ball" platform developed by the US Army allows for a single injection to produce antibodies against twenty-four different variants. Now that we know it is passing between mammals and mutating in them, that multi-variant vaccine platform seems to have been prophetic.