>>14048086So a more dangerous variant could develop in someone, but it would have to out-compete Omicron, which may be possible if it develops the ability to bypass all immunity. I think that's unlikely though because once most of the world's population has immunity, infections are going to be more isolated and sporadic rather than coming in waves, which means far fewer opportunities for mutations to occur. Also, immunity from infection is very broad, so it's unlikely a variant will emerge that can bypass immunity enough to be very deadly. Children could be at greater risk, but kids have excellent mucosal immunity, so they'll probably get a cold after first exposure and be fine. Remember that the majority of the population had no pre-existing immunity to SARS-CoV-2, which will never be the case again. Short of ADE, I don't see much risk going forward.
>Don't you think this will become like a cyclical cold but it's the final wave instead?I think it's the final major wave and we'll deal with sporadic infections, similar to the other endemic coronaviruses. Immunity will wane faster in some people than others, SARS-CoV-2 may cause some sniffles, their immunity will be boosted, repeat again in several years.
