>>13944237Questions for Influenza
(1) Why is influenza both seasonal and ubiquitous and where is the virus between epidemics?
(2) Why are the epidemics so explosive?
(3) Why do they end so abruptly?
(4) What explains the frequent coincidental timing of epidemics in countries of similar latitude?
(5) Why is the serial interval obscure?
(6) Why is the secondary attack rate so low?
(7) Why did epidemics in previous ages spread so rapidly, despite the lack of modern transport?
(8) Why does experimental inoculation of seronegative humans fail to cause illness in all the volunteers?
(9) Why has influenza mortality of the aged not declined as their vaccination rates increased?
Hope-Simpson (1992) & Connel et al (2008)
