What does this mean?
https://twitter.com/georgimarinov/status/1466849682852880384
https://twitter.com/fitterhappierAJ/status/1466973331714940933
"Cov2 could evolve to bind to our ace2 receptor better than our antibodies can interfere with it"

https://www.biorxiv.org/content/10.1101/2021.01.06.425392v3

Further in vitro evolution enhancing binding by 600-fold provides guidelines towards potentially new evolving mutations with even higher infectivity. For example, Q498R epistatic to N501Y.

What happens as covid increases in ACE2 binding affinity past antibody binding? Does all natural immunity fail?

According to experts the virus is highly selective for ACE2 binding affinity and each new successful mutant is pretty much better / picking up major affinity each generation. his theory is that over time it will reach a tipping a point and herd immunity will continue to fail

Can someone explain this