Spike protein: furin cleavage insert
No.13895251 ViewReplyOriginalReport
Quoted By: >>13895265 >>13895273 >>13895292 >>13897258
So they inserted PRRA between S and R
NS - PRRA - R
to get RRAR which is the furin cleavage site.
But why did they need to insert P?
RRA would suffice, no?
Also how do we know that RRAR is the furin cleavage site? It's just 4 random amino acids. How did they determine their purpose? Also there is another cleavage done at S2' by TMPRSS2 that facilitates fusion. Why doesn't anyone talk about that one?
NS - PRRA - R
to get RRAR which is the furin cleavage site.
But why did they need to insert P?
RRA would suffice, no?
Also how do we know that RRAR is the furin cleavage site? It's just 4 random amino acids. How did they determine their purpose? Also there is another cleavage done at S2' by TMPRSS2 that facilitates fusion. Why doesn't anyone talk about that one?
