Digital immortality.
Computers so advanced they replicate individual humans not equally but better than any biological cloning. The cyber double will be consummately indistinguishable from the "original", its biological counterpart, to a degree that every contemporary human will find beyond sufficient in order to relate to it in absolutely no distinct manner whatsoever. Not by social engineering but by the wholy comprehension that such distinctions are mere mindless prejudices out of profuse ignorance. Organic becomes nothing but an incidental term of historical relevance, if that.
Are you ready to the death of death?