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Nietzsche lamented the death of god.
He saw that eventually, the darwinian revelation (which many had inferred throughout history) was finally going to sink in for most men. This is what we are experiencing right now, and people do and will continue to give up.
Humanism is obviously not nearly as strong as the promises of religion, and religion is impossible to believe in for more and more all the time. This is a real issue, We probably will no longer be able to maintain a civilization.