>>13836497>What about enzyme production and pre-digestionWhat about them? Your GI tract is a highly tuned fermentation chamber that's several dozen feet long. Your gut microbiome already produces a staggering array of extra-cellular enzymes to hydrolyze indigestible fiber.
Look at the variance in the immunological readouts in the arxived paper in
>>13836299. The fermentation products are driving a tiny fraction of that explained variance. There's also a lot of regression to the mean that's going on with the changes in ASV relative abundance that they don't discuss.
