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Neanderthals are hominids in the genus Homo, humans, and generally classified as a distinct species, H. neanderthalensis, although sometimes as a subspecies of modern human as H. sapiens neanderthalensis. This would necessitate the classification of modern humans as H. s. sapiens.[8]
A large part of the controversy stems from the vagueness of the term "species", as it is generally used to distinguish two genetically isolated populations, but admixture between modern humans and Neanderthals is known to have occurred.[8][121] However, the absence of Neanderthal-derived patrilineal Y-chromosome and matrilineal mitochondrial DNA (mtDNA) in modern humans, along with the underrepresentation of Neanderthal X chromosome DNA, could imply reduced fertility or frequent sterility of some hybrid crosses,[78][122][123][124] representing a partial biological reproductive barrier between the groups, and therefore species distinction.[78]
In 2014, geneticist Svante Pääbo described such "taxonomic wars" as unresolvable, "since there is no definition of species perfectly describing the case".[8]