What is the current scientific explanation for women turning batshit crazy pre-menstrually or post-partum?

Currently accepted disorders:
>pre menstrual dysphoric disorder
>post partum blues/depression/psychosis

(So far 100% of the individuals I have observed exhibited prominent mood changes during menstruation, with some bordering pathological levels).

There is this known relationship between estrogen levels and neurotransmitters. And apparently female schizos/bipolars get worse symptoms in estrogen lows and require less medications on peaks, however studies are small and are not conclusive.

Is maxxing on estrogens a valid preventive psychiatric treatment?