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Perhaps some chemical/hormone found which can change human behaviour in some dramatic way. Or something like a psychadelic yet acts differently in some way which is beneficial for us, like being able to concentrate for much longer, or being able to control your body to a greater degree like for weight loss
Neuralink may find some compatability with the brain which opens up another field of brain research, could be that generation 2 or 3 or neuralink may allow scientific measurement of dreams, thoughts, emotions
There may be something obvious in space that we haven't been looking for, and upon discovery it may change the way we see the universe
Bigger particle collider may find some interesting new subatomic particles with useful properties, or grants us knowledge to manipulate normal matter in a beneficial way
Each new peak climbed with AI will also seem like it's own big discovery I think, at least in usefulness in everyday life
