How do we increase height after puberty?
The science made a good step recenlty regarding the human growth. It is discovered now that human growth can be enhanced with other ways than HGH and hormones which acts on general areas and can lead to side effects . Now many factors are being researched that acts direcly on the growth plate itself ( I3O , CNP etc )
The science has also recently discovered that our understanding of human growth was not true , as a matter of fact scientists has now proven that in the growth plate there are still stem cells niche , so saying growth plate are 'dead' or "closed" is not true. The thing is that during growth those stem cells are differentiating in chondrocytes, whilch themselves proliferate and with hypertrophy becomes bones. The problem is that the 'available' stem cells that turn to bone are thought to be limited ( something that nature/genetic determines ) so people with larger amounts of possible chondrocytes will get taller.
Now what is promosing is that if science discovers :
1- a way to make the inactive stem cells in the closed plates turn to chondrocyte
2- a way to enhance the chondrogenesis and make bones out of these chondrocytes
3- target these methods to the growth plate
then we will be able to see people having their growth plates 'open' again and will go through puberty again.
Something like this won't be availble before 10 years, because even if they find out a way to do this they still need 4 to 5 years for clinical trials and make sure the treatment is approved and presents no risk.
Moreover, such a treatment will be probably usefull for people with significant short stature. Otherwise Imagine if the person who is 5'7" will want extra 2 inches then also the person with 6'1" will also want some extra inches and shorter people will remain short and taller people will remain tall.
The science made a good step recenlty regarding the human growth. It is discovered now that human growth can be enhanced with other ways than HGH and hormones which acts on general areas and can lead to side effects . Now many factors are being researched that acts direcly on the growth plate itself ( I3O , CNP etc )
The science has also recently discovered that our understanding of human growth was not true , as a matter of fact scientists has now proven that in the growth plate there are still stem cells niche , so saying growth plate are 'dead' or "closed" is not true. The thing is that during growth those stem cells are differentiating in chondrocytes, whilch themselves proliferate and with hypertrophy becomes bones. The problem is that the 'available' stem cells that turn to bone are thought to be limited ( something that nature/genetic determines ) so people with larger amounts of possible chondrocytes will get taller.
Now what is promosing is that if science discovers :
1- a way to make the inactive stem cells in the closed plates turn to chondrocyte
2- a way to enhance the chondrogenesis and make bones out of these chondrocytes
3- target these methods to the growth plate
then we will be able to see people having their growth plates 'open' again and will go through puberty again.
Something like this won't be availble before 10 years, because even if they find out a way to do this they still need 4 to 5 years for clinical trials and make sure the treatment is approved and presents no risk.
Moreover, such a treatment will be probably usefull for people with significant short stature. Otherwise Imagine if the person who is 5'7" will want extra 2 inches then also the person with 6'1" will also want some extra inches and shorter people will remain short and taller people will remain tall.
