Quoted By:
>FOXDIE was an engineered retrovirus developed by the DIA for the Pentagon. It was programmed to kill specific people by recognizing a person's DNA, causing cardiac arrest.
>The FOXDIE virus enters macrophages in the target's bloodstream, then uses enzymes (integrase, primarily) to integrate its genetic material into a DNA sequence that it has been "programmed" to recognize (this last part being the difference between it and an ordinary retrovirus, which may display a tendency to integrate at certain sites but cannot be "programmed" to target specific sequences exclusively). Once this genetic material is integrated into the host cell chromosome, it promotes TNF (tumor necrosis factor) epsilon production in the host. The TNF-? is carried along with the blood, to the heart, where it binds to the TNF receptors, causing apoptosis in myocardial cells, which in turn leads to the victim suffering a fatal heart attack. The only difference between this and natural heart attacks is that the latter occur when the heart cells die from lack of oxygen and sugar, usually caused by a blocked coronary artery, rather than TNF-?-induced apoptosis. Rate of progression increases with age. Older infected targets will see manifestation of FOXDIE much more rapidly than the young.
