>>13532035>If you believe the spike-protein damage occurs during conformational changes, then a prefusion-stable spike protein should allay those concerns. not really, i would like to see empirical evidence of stabilization of the prefusion structure during binding for a large sample of the hexapro modded spikes. also given we're talking about a few amino acids, it is possible that translation errors occur where something other than proline is at that position screwing the whole thing up. and iirc translation is the most error-prone step of protein synthesis. also qc of synthesis of the mrna strand, all it takes is misplacing one of those first 2 cytosines with another nucleotide and fail.
>and the problem here is that it's possible to doubt people all the way down to rock bottom.well yes, you shouldn't trust anyone ever. especially when profit is involved which should be a conflict of interest for obvious reasons.
>f your concern is damage during ACE-2 binding alone (which seems more in line with the Salk study)we get binding with hexapro modded spikes, they even show that with spr.
>there the medical community makes an "injection-site locality" and "limited amount" argument. the injection site locality was shown wrong in the rat model. so it fails before humans even get into the picture. maybe it's different for humans, i have yet to see but it's not looking good already.
>Anti-vaxxers saw this as a cover-your-ass responsewhich really looks like it is the case as when a scientific consensus is established even if prematurely, anything that even seemingly goes against it can be reputation destroying.
>Of course, "limited amount" may seem like a hand-waving response. After all, how long is a length of string?you can have an empty string. ;^) and no i'm not advocating homeopathy here. just being autistic.
