Semen retention

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Are there any studies on the effect of orgasm on the male hormonal profile? Thinking about it instinctively it would seem like orgasm leaves the body weaker than it was before. If we think about Dawkins The Selfish Gene, our genes only care about one thing and that's to reproduce; orgasm inside a female. Once we have done this I would assume that the body no longer feels the need to be in optimal shape (hormonal profile, inflammation response etc) because it has accomplished its sole mission. Semen retention makes the body anxious to orgasm so it ramps up everything it got to put us in the most optimal shape, psychically and mentally, to do what it wants to do.

Is there any truth to this?