Just wait until Al Qaeda realizes that small pox can be resurrected. Given that they have a few competent biologists, they can unleash small pox around the world. It is airborne and very contagious. I think the death rate is like 60-90%, a very slow, painful, and visually horrifying death. Even if you survive, you're left with scars covering your body for the rest of your life.
The way I see it, small pox WILL come back one day, even if it's from an accidental explosion in the Russian facility where they store samples of the live virus. Or some asshole frees the samples stored in the US as a /pol/ joke.
Just kidding, you can't resurrect small pox! sorry for the big fake health scare.