So every one of our cells has the full genome, but our epigenome is responsible for which genes are turned off and on in a given cell. This gives the specific cell it's identity. For example the epigenetic profile of a ?-cell in the pancreas makes it so it's insulin gene is turned on, while the insulin gene in a skin cell is turned off. The epigenome determines what functions a cell has.
Let's say we have the penis of a 15 year old male and the penis of a 25 year old male. They will probably look similar in structure but the 15 year old penis will have a couple of other functions, most importantly in this case: it can grow when stimulated by the right hormones. It grows because the epigenetic profile it has has the genes that result in growth turned on (whichever those genes are).
So can you make cells return to a younger epigenetic profile? It has been done in rat optic neurons by insterting 3 genes that produce yamanaka factors. The epigenome of these rats was observably younger (We can measure this with great accuracy, see Horvath's clock) AND they regained various functions in that they could regenerate like neurons of a young rat (adult nerve cells regenerate VERY slowly, this is true in humans too which is why nerve damage almost always is near permanent). The rat neurons were rejuvenated, essentially. This is recent tech from like december 2019. Human trials of this technology are beginning in 2022.
Now the idea is this:
>Use yamanaka factors to make tissues in the penis regain their growth function
>Treat the subject with the correct hormones to stimulate growth of the penis
>Repeat until satisfactory results are had
There is a lot of money to be made here, so it is most likely coming quite soon.
Let's say we have the penis of a 15 year old male and the penis of a 25 year old male. They will probably look similar in structure but the 15 year old penis will have a couple of other functions, most importantly in this case: it can grow when stimulated by the right hormones. It grows because the epigenetic profile it has has the genes that result in growth turned on (whichever those genes are).
So can you make cells return to a younger epigenetic profile? It has been done in rat optic neurons by insterting 3 genes that produce yamanaka factors. The epigenome of these rats was observably younger (We can measure this with great accuracy, see Horvath's clock) AND they regained various functions in that they could regenerate like neurons of a young rat (adult nerve cells regenerate VERY slowly, this is true in humans too which is why nerve damage almost always is near permanent). The rat neurons were rejuvenated, essentially. This is recent tech from like december 2019. Human trials of this technology are beginning in 2022.
Now the idea is this:
>Use yamanaka factors to make tissues in the penis regain their growth function
>Treat the subject with the correct hormones to stimulate growth of the penis
>Repeat until satisfactory results are had
There is a lot of money to be made here, so it is most likely coming quite soon.
