Hello /sci/ I propose an experiment.
Let's setup a robotic warehouse filled with mouse habitats each capable of housing 100 mice. At some time interval lasting approximately ten generations the mice in a habitat are collected, tested for fitness and then genetically analyzed, those that contain some mutation matching the human genome are matched with others likewise selected and breeding pairs are seeded into freshly sterilized habitats. Those that do not contain such a mutation or are otherwise unfit are purged, perhaps recycled into onions to feed the others.
Let's for the sake of argument presume there are on average 5×10^?9 germline mutations per bp each generation; there are 3 billion base pairs; we share 97.5% in common with mice at the beginning of the experiment.
How many habitats would it take to have mice that share more than 99% of our genome (more closely related than chimpanzees) after running the experiment for 20 years.
Let's setup a robotic warehouse filled with mouse habitats each capable of housing 100 mice. At some time interval lasting approximately ten generations the mice in a habitat are collected, tested for fitness and then genetically analyzed, those that contain some mutation matching the human genome are matched with others likewise selected and breeding pairs are seeded into freshly sterilized habitats. Those that do not contain such a mutation or are otherwise unfit are purged, perhaps recycled into onions to feed the others.
Let's for the sake of argument presume there are on average 5×10^?9 germline mutations per bp each generation; there are 3 billion base pairs; we share 97.5% in common with mice at the beginning of the experiment.
How many habitats would it take to have mice that share more than 99% of our genome (more closely related than chimpanzees) after running the experiment for 20 years.