Currently, the cutting-edge philosophy on conducting better responses to diseases includes adapting the immune system to target various dangerous viruses, bacteria, and even cancer cells, all of whom express various antigens on their outermost layer of structure which the immune system cells can bind to and conjure an effective response to eliminate the target. But the array of evolutionary responses is incalculably vast, is there any reason why evolution could not develop a "dummy layer" over these contagious particles while preserving an exit mechanism so that the immune system exhausts its resources on a useless target?

What do you think /sci/? Is the future of antibotic resistance contained not within chemical defenses but rather in physical, 3D defenses against the immune response? Is evolution just too slow for us to see this mechanism in real life organisms? This seems like a tremendous upgrade to the defenses currently available to these organisms.