No.13264096 ViewReplyOriginalReport
>Neurobiology of Disease, Volume 146, 2020.
>"The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier"
-"In our study we showed that even SARS-CoV-2 spike protein alone is a potent inductor of endothelial dysfunction and that manifestations of COVID-19 shock syndrome in children can be at least partially attributed to its action."
-"productive viral infection of endothelial cells is not an absolute requirement for endothelial dysfunction, as it also can arrive as a result of viral protein shedding."

>Journal of Vaccines Volume 9, 2021.
>"SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines"
-"Thus, it is important to be aware that the spike protein produced by the new COVID-19 vaccines may also affect the host cells. We should monitor the long-term consequences of these vaccines carefully, especially when they are administered to otherwise healthy individuals."
-"Kuba et al. [28] showed that the injection of mice with recombinant SARS-CoV-1 spike protein reduced the ACE2 expression and worsened the acid-induced lung injury."
-"The SARS-CoV-2 spike protein without the rest of the viral components has also been shown to activate cell signaling by Patra et al. [29]"