>>96347560>>96289785 here, I'll bite.
I started shipping Spidey and Darkstalkers' Felicia because I'd been interested in what sort of crossover ships would work with Peter, after having seen art for PG x Spidey, and I gravitated towards MvC. Morrigan and Spider-Man... I wasn't too enthused with since it felt like it'd more or less play out like Peter and Felicia's relationship did, sans the psycho ex bit... and then I saw Felicia, and it all clicked into place.
Like these guys (>>96294659
) have stated, a relationship between these two would be much more emotionally investing. They both face discrimination for who or what they are, and persevere in spite of it. Peter would wrestle with feelings of inadequacy due to Felicia being, well... FELICIA, and you can bet your ass Felicia wouldn't have any of that moping, no sir.
There's also the implications that Felicia's perpetually happy-go-lucky can-do attitude is something of a mask she's crafted due to years of discrimination, and probably contributed towards her desire to see Darkstalkers and humans coexist, and why she wants to help others whenever she can. I figure that having an actual relationship with Peter would allow her to be a little more vulnerable sometimes, and drop the mask around him. Maybe even have her vent to him on occasion, too.
There's also the fact that the people that associate with both characters would inevitably meet. Like Felicia's fellow Catgirls and Jon Talbain, as well as Spidey's multiple associates and Peter's friends. It'd definitely make for one hell of a story, I think.