>>122038492This happened in one of those alternate universe books where a cannibal virus was loose on the planet. Frank was immune because he was patient zero (russians tried to bring the virus in, Frank killed them, got splashed with the vials while the rest washed away and got into the ecosystem), and Cap took longer time to get affected because he was Cap. Eventually, Cap feels he is changing and begs Frank to not let him becoming the enemy, Frank tells him he was always his hero.
The funnier part was when Wolverine's resistance tried to stop the Hulks cannibal tribe.
Wolverine: "Okay, the science team needs an hour to pack up their transports. No matter what happens, we must give them that hour.
Hulk: "KILL THEM. EAT THEM."
Wolverine: "Yeah, I know, his speech was better."