Honestly, while Spidey can have his pick of any of the Capcom gals, I'm definitely partial to Spidey x Felicia.
Like... Morrigan's great, but she's not one to commit to a long term relationship, and would probably have trouble wrapping her head around Spidey, his sense of morals, and why he does what he does. She'd basically be a more supernatural Black Cat, ironically.
Chun-Li's also a pairing I see here and there; I can definitely see a sort of camaraderie akin to what Spider-Man and Yuri had in the PS4 game prior to Yuri going MAXIMUM EDGE. She'd definitely sympathize with Peter were ever comfortable enough to tell her why he goes out and fights crime, and would likely be one of the few individuals among INTERPOL that would tolerate his skirting of the law with his vigilantism.
Q-Bee would just see him as lunch, and that's not even getting into the whole Spiders vs. Wasps bullshit in the actual comics with Shathra.
Juri would probably find Spider-Man interesting... in the way some predators like a good chase before they tuck in for their meal. Spidey would avoid her like the fucking plague.
What other Capcom gals has he been shipped with?