imo it wouldnt do anything.
I think Wolverine's regeneration doesn't work exactly how regeneration would, if it does every time that Wolverine would get burned/toasted his hair should be completely Bald and wait for X amount of months for it to grow back to how it was pre-burned.
but every incarnation of Wolverine who had been put in such scenarios resulted in him regenerating back to how he was before he got toasted, minus the clothes of course.
This led me to believe that instead of regenerating damage parts, his regeneration works by having a 'saved state' and each regeneration is going to back to that state, not less, not more.
This also leads me to believe that Wolverine and other similar mutants wont have any benefit from lifting weights, as lifting weights aims to increase in muscle mass, Wolverine's regeneration would just revert back to the saved state.
I think the saved state is acquired at their prime.
