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Gonna post the same thing I posted in the "best cartoonist of all time" thread. To be an animator you gotta have three skills (each composed out of other skills):
1. Draftsmanship. You have to be able to translate what you see in your mind to a drawing on paper. This involves solid drawing, perspective, anatomy, linework, shading, and so on. OP's pic definitely has draftsmanship.
2. Timing. This involves knowing how people and objects move so when you draw multiple frames (animation) things move in a believable and expressive way. OP's pic is taken from a shot where Harley moves with way too much ease-in and ease-out (settle), making what's supposed to be a determined, sharp gesture a wobbly, weird gesture.
3. Life drawings, or posing and facial expressions. This is important so when you draw something with good draftsmanship and good timing, you also draw something expressive and emotive and interesting, and so on. Anime in general relies way too much on templates (^_^) (T^T) and predefined poses and expressions, resulting in a very samey feel.
Anime generally has good draftsmanship and piss-poor timing and very repetitive and derivative posing and expressions.