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it's hard to disagree or disprove something that's been misinterpreted so hard.
It's like the whole "no politics in games" bullshit, before you can have an honest discussion about it you need to get through a lot of semantics and figure out what you think it means, vs. what others think it means.
Same with this. Completely ignore that a good deal of trans people don't pass that well, and the few that do a lot of people might not even want to fuck because the business end is not to their preference. Doesn't mean trans people can't look nice, or hot, or attractive, but there will be those who find out someone's trans and just be completely turned off.
Shit like this comic then serves no other point than to be lazy point-scoring, only fit to advance the author's social position among their peers who share their views and prejudices, and will ultimately hurt the perception of trans people more than it helps them. Good comic.